ETV3 and Hodgkins lymphoma: In the following, we focused on ETS gene ETV3, downregulated in normal B-cell development (Fig 1) and aberrantly activated in 4/17 (23%) HL patients of dataset GSE12453 including classical HL and NLPHL, and in 2/29 (7%) classical HL patients of dataset GSE39134 (Fig 2A).