CDK1 and cancer: CDK1, the founding member of the cyclin‐dependent protein kinase (CDK) family, is frequently overexpressed in various human cancers and is strongly associated with malignant phenotypes and poor prognosis.[27] Evidence suggests that the upregulation of CDK1 is due to copy number variation.[28, 29] However, no statistical difference in the copy number of CDK1 was observed between oxaliplatin‐resistant and oxaliplatin‐sensitive CRC tissues, suggesting the existence of other mechanisms that regulate CDK1.