The positive correlation between the FoxP3 + TIL count and the CD68 + and CD163 + TAM counts may reflect the existence of a pro-tumoral microenvironment in HER2 + breast cancer, as Tregs and especially the M2-like (CD163 +) TAMs, contribute to the creation of inflammatory conditions promoting tumor progression [10, 13]. Here, ERBB2 is linked to neoplasm.