The results (Fig. S3) revealed that the abundance of enzymes such as 6-phospho-beta-glucosidase (EC 3.2.1.86), beta-d-fucosidase (EC 3.2.1.38), and ABA-specific beta-glucosidase (EC 3.2.1.175) was significantly decreased in BD (P < 0.05), while the abundance of enzymes such as alpha-l-arabinofuranosidase (EC 3.2.1.55), beta-xylosidase (EC 3.2.1.37), and alpha-glucosidase (EC 3.2.1.20) was significantly increased in BD (P< 0.05); collectively, these enzymes likely play a key role in carbohydrate catabolism and metabolism. Here, GAA is linked to Behcet disease.