Table 1 lists the characteristics of the patients categorized by serum magnesium centile subgroups according to the knots. In the overall population, the mean age of 54.3 ± 15.2 years, and 60.1% were male. The mean serum magnesium level was 1.12 ± 0.21 mmol/L. There were significant subgroup differences in age, sex, educational level, HD vintages, vascular access, diabetes mellitus, CHD, mean arterial pressure, waist circumference, hip circumference, hemoglobin, serum albumin, creatinine, uric acid, potassium, calcium, iPTH and hs-CRP levels (all P < 0.05). The gene discussed is MAP3K14; the disease is diabetes mellitus.