Freshly excised bone-proximal tumors from 122 patients (107 sarcomas and 15 carcinoma bone metastases) were taken through the pipeline to obtain information on mutational burden, MHC haplotype and neo-epitopes (Figure 1A), clonal expansion of TILs (Figure 1B), immune cell infiltrates of tumors (Figure 1C), and CD91 expression (Figure 1D). This evidence concerns the gene HLA-C and sarcoma.