IL17A and invasive breast carcinoma: The difference between serum IL-17A concentrations in women with early invasive breast cancer preoperatively and after three cycles of adjuvant chemotherapy or three months of endocrine therapy is shown in Table 3 and Figure 4. A significant decrease in the serum IL-17A concentration was observed after surgery during adjuvant therapy, compared to the preoperative values, (P<0.001).