ERBB2 and neoplasm: The spatial distribution of the nanoparticles was then compared to that of blood vessels present in the tumor identified by endothelial cell marker CD31, proinflammatory and dendritic cells using CD11c, tumor cells with HER2 staining, macrophages identified using F4/80, fibroblasts using alpha smooth muscle actin (SMA) and collagen by Masson's Trichrome staining.