When comparing the three beforementioned SNPs’ allele distribution among the two groups; the mutant allele of the ACE-1 rs4343 SNP and the wild allele of the ACE-2 rs908004 SNP were found to significantly more predominant in the severe COVID-19 patients than the non-severe COVID-19 patients, as shown in Table 5. The gene discussed is ACE2; the disease is COVID-19.