Moreover, Quercetin might upregulate expression of GAP43, promote neurite outgrowth and regeneration of DRGs neurons and PC12 cells (Chen et al., 2015; Katebi et al., 2019), enhance the proliferation and migration of Schwann cells, improve locomotor function recovery, axonal regeneration and energy metabolism after spinal cord injury (SCI) (Wang et al., 2020). Here, GAP43 is linked to spinal cord injury.