Finally, the results of “ssGSEA” score showed that five tumor-related pathways were significantly different between two clusters, including WNT, TP53, PI3K, NRF1, and HIPPO, which have been linked to the development and progression of cancer and have great potential in predicting the prognosis of TNBC patients (Figure 4C). The gene discussed is NRF1; the disease is cancer.