In this context, two important actions can be related to GH: an action like that of insulin characterized by hypoglycemia, increased protein synthesis, glycogenesis, and lipogenesis; and another late action, in which the opposite occurs, with hyperglycemia, hyperinsulinemia, increased lipolysis, and reduced glucose metabolism, corresponding to the primary physiological effects related to GH (2). This evidence concerns the gene GH1 and hyperinsulinism.