ITGAM and neoplasm: After B16F10-OVA tumor cell injection, lungs from both B6 wildtype and E2-/- mice possessed similar frequencies of CD103+ DCs, CD11b+ DCs, alveolar and interstitial macrophages (Figure 1E), with a concomitant 50-60% loss of total lung monocytes due to loss of nMo (26) (Figure 1A and Supplemental Figure 1A).