Next, we carried out a comprehensive meta-analysis, including seven autoimmune diseases (T1D, SLE, GD, HT, RA, MS, and AAD), three SNPs of IFIH1 (rs1990760, rs3747517, and rs10930046), and three ethnicities (Caucasian, Asian, and African), to investigate whether IFIH1 polymorphisms were associated with AID susceptibility. Here, IFIH1 is linked to autoimmune disease.