CXCL10 and familial hypercholesterolemia: To examine the association of continuous IP-10 levels with myocardial function improvement (ΔLVEF), we used multivariable linear regression analysis adjusting for randomized intervention (cyclosporine vs. placebo), age, sex, body mass index, traditional cardiovascular risk factors including diabetes mellitus, arterial hypertension and hypercholesterolemia, as well as high-sensitivity cardiac troponin T (hs-cTnT) (Table 3).