To further evaluate, whether the KLRC2wt/del allelic configurations are associated with the development of EBV+ lymphomas, we co-cultured EBV-infected K562-CR2-HLA-E*0103/0103 or K562-CR2-HLA-E*0101/0101 cells together with NKG2A-NKG2C+ NK cells, isolated from 12 HCMV-seropositive donors, encoding for the KLRC2wt/wt (N=6) and KLRC2wt/del (N=6) variants. This evidence concerns the gene KLRC1 and lymphoma.