The area under the curve (AUC) values for 6 shared hub genes (CDC6, PLCG1, KIF15, LCK, CDC25C, and RASGRP1) in the SLE dataset to discriminate between patients and healthy controls were greater than 0.61 (Figure 9B), while those for the COVID-19 dataset were greater than 0.91 (Figure 9A). This evidence concerns the gene PLCG1 and systemic lupus erythematosus.