HLA-DQB1 and rheumatoid arthritis: On the other hand, our data showed that the significant frequent alleles of HLA-DQB1 identified in RA patients were HLA-DQB1*03 (P = 0.000, OR = 3.43), whereas in controls, was HLA-DRQB1*02 (P = 0.02, OR = 0.58) and *06 (P = 0.00, OR = 0.42).