To test whether the aberrant expression of Morrbid in monocytes is CAD specific or is a general molecular phenomenon in human monocytes with the enhanced differentiation from monocyte to macrophage, we also determined the Morrbid expression levels in monocytes from patents with sepsis, which is another human disease with the enhanced monocyte–macrophage differentiation. The gene discussed is MIR4435-2HG; the disease is Sepsis.