Polymorphisms in TLR2 and TLR4 genes were discussed to influence the onset of allergic diseases, although a case-control study including atopic children with asthma, children suffering from non-atopic asthma and children with AR did not find a significant association between these two TLRs and allergic disorders, but an association with the disease ́s severity was suggested (Hussein et al., 2012). This evidence concerns the gene TLR4 and asthma.