This designed nano-biosensing platform exhibits a broad detection range with high sensitivity and a significantly lower detection limit, which is a potent biosensor for the detection of cardiovascular disease biomarkers.74 Similar biosensors fabricated of nitrogen-doped rGO exhibited a good ability to detect cardiac troponin I in concentrations of less than 1 pg/ml and offering great applicability in sensitive screening and routine monitoring of cTnI in clinical scales.75 The gene discussed is TNNI3; the disease is cardiovascular disorder.