The top 5 hub genes of the yellow module (see Tables A2, A3 for the 20 genes and their biotypes with the highest kME values in ranked order) included AHRR, LINC00599, SEMA6B, TMEM45B and CTTNBP2. Of note, AHRR was previously implicated in a large PTSD epigenome-wide association study (6). The gene discussed is SEMA6B; the disease is post-traumatic stress disorder.