CRHR1 and major depressive disorder: Among the 39 SNPs that were shared between MDD and hospitalized COVID-19 (Supplementary Table S3), the most significant (rs17689471 at locus 17q21.31, Pmeta = 1.48 × 10−12) and second significant SNPs (rs17689824 at locus 17q21.31, Pmeta = 1.64 × 10−12) were both located at CRHR1. In addition, among the shared SNPs between MDD and COVID-19 infection (Supplementary Table S4), the most significant one (rs853676 at locus 6p22.1, Pmeta = 2.74 × 10−10) was located at ZSCAN31.