AKI genes (Havcr and Lcn2) were elevated on days 1 and 6, and fibrosis genes (Col1a1, Col1a2, Col3a1, and Fn1) on days 6 and 20 of kidney I/R (Figures 1C,D, Supplementary Figure S1A). The gene discussed is COL3A1; the disease is acute kidney injury.