Genetically predicted meningiomas were associated with levels of interleukin-16 (IL-16) (BETA = −0.037, 95% CI = −0.069 ~ −0.004) and interferon gamma-induced protein 10 (IP10) (BETA = 0.036, 95% CI = 0.003–0.068) using IVW methods. This evidence concerns the gene IL16 and meningioma.