GAS5 is a long non-coding RNA expressed throughout the body originally found to have tumor suppressor activity by arresting the growth cycle of stressed cells, but also promotes apoptosis and acts to remove micro-RNA, ultimately decreasing glucocorticoid-dependent transcription of genes; it essentially acts as a decoy glucocorticoid response element (GRE) within the cell nucleus (Petta et al., 2016; Yu and Hann, 2019). This evidence concerns the gene GAS5 and neoplasm.