MBOAT7 and metabolic dysfunction-associated steatotic liver disease: (18) discovered that MBOAT7 deletion in hepatocytes can lead to the disruption of the intracellular PI side-chain remodeling pathway, which in turn promoted the pathological progression of liver fibrosis by upregulation of ECM genes in a high-fat, methionine-low, choline-deficient diet-fed mouse model of NAFLD.