Mutations in two IDA heavy-chain protein-encoding genes, DNAH1 (MIM: 603332) and DNAH2 (MIM: 603333), and two ODA heavy chain components, DNAH8 (MIM: 603337) and DNAH17 (MIM: 610063), have been described in individuals with isolated male infertility due to asthenoteratozoospermia. Here, DNAH8 is linked to male infertility.