In clinical samples, the NLRP11, vimentin, and vimentin‐K104Ac were detected in LUAD tissues at different tumor node metastasis (TNM) stages using IHC, and the results demonstrated that the expression of NLRP11 and vimentin‐K104Ac in distant metastatic foci from stage IV patients was markedly higher than that in primary foci (Figure 3M; Figure S4F,G, Supporting Information). This evidence concerns the gene VIM and neoplasm.