Such complexes facilitate interactions between TG2‐specific B cells and gluten‐specific CD4+ T cells, leading to the generation of TG2‐specific plasma cells as well as clonal amplification of long‐lived gluten‐specific T cells.[23] TG3‐specific antibodies are likely formed through a parallel mechanism involving gluten‐specific T cells and TG3–gluten complexes formed in DH patients under conditions that are not known. Here, CD4 is linked to dermatitis herpetiformis, familial.