FLT3 and chronic myelogenous leukemia, BCR-ABL1 positive: Indeed, various oncogenes, such as BCR-ABL1 or FLT3-ITD, were reported to support high levels of basal autophagy sustaining cell proliferation and leukemogenesis in chronic myeloid leukemia (CML) or in acute myeloid leukemia (AML), respectively [13–15].