To name a few other examples Aminoguanidine (Inhibits the accelerated death of retinal capillary cells and development of retinopathy, inhibits lipid peroxidation and AGEs formation); Lipoic acid (Attenuates the apoptosis of retinal capillary cells and acellular capillaries, decreases the levels of nitrotyrosine, VEGF and oxidatively modified proteins, activation of NF-kB) and Vitamin C/E (Reduce neovascularization, prevent the inhibition of retinal GR, GPx and SOD activities) have also shown positive properties on the DR [46]. The gene discussed is SOD1; the disease is retinal disorder.