ADGRV1 and Usher syndrome: 12 USH2B has been mapped to 3p23-p24.2; however, the gene has not been identified13. USH2A is also the most common gene to cause nonsyndromic autosomal recessive RP; thus there is substantial information about its disease mechanism and associated phenotypes9. ,14, 15, 16 In stark contrast, there are limited data about ADGRV1-associated USH in the literature.