In addition, another study has also shown that CFDTW can serve as a PCOS treatment drug by decreasing the serum levels of TCHO, TG, LDL-c, LH, T, IL-1β, IL-6, and TNF-α, while increasing those of HDL-c in a dose-dependent manner [33], which is in agreement with our results that CFDTW treatment restored the estrous cycle, reduced the serum levels of T and LH in PCOS rats. This evidence concerns the gene TNF and polycystic ovary syndrome.