Similarly, CEA (Fig. 3C) was positively correlated with tumor differentiation (P/r =  < 0.001/0.325), lymph node metastasis (P/r = 0.004/0.203), tumor size (P/r = 0.012/0.176), and tumor type (P/r = 0.016/0.169) in CRC patients. Here, CEACAM5 is linked to metastatic malignant neoplasm in the lymph nodes.