CTLA4 and neoplasm: ELISPOT results elucidated that an elevated number of IFN-γ secreting spot forming was witnessed in the DC/tumor fusion+LPS‐Nb36 groups in contrast to those in the DC/tumor fusion, DC/tumor fusion+anti-CTLA-4 mAb, DC/tumor fusion+LPS-CTLA-4 mAb and DC/tumor fusion+Nb36 groups after being challenged with corresponding target cells (Fig. 4A).