One of the tumours with discordant scoring among the non-majority diagnoses showed a clustered pattern of expression (small 3+ focus within a majority negative score 0 tumour), Fig. 2c, Fig. 2dE and F. It is of note that further sampling from a metastatic axillary lymph node showed only a HER2 0 profile. Here, ERBB2 is linked to neoplasm.