UBA1 and malignant colon neoplasm: Remarkably, UBA1 emerged as the most crucial gene among them, as illustrated in Figure 5A. In order to further scrutinize the expression of UBA1 in colon cancer, the UBA1 mRNA expression data was sourced from several databases such as TCGA and GEO (GSE110225, GSE9348, GSE103512, and GSE106582).