In the multivariable analysis, patients who are female (OR 0.75, 95% CI 0.62–0.91), with the marital status of married or cohabitating (vs. single: OR 0.77, 95% CI 0.70–0.84), with a BMI below 18.4 (vs. BMI = 18.5–24.9 OR 0.86, 95% CI 0.76–0.97), with low CD4 count at ART initiation or with opportunistic infection were less likely to delay ART initiation, while PWID (vs. homosexual: OR 6.53, 95% CI 3.84–11.10), patients with HBV/HCV seropositive and with tuberculosis were more likely to delay ART initiation. The gene discussed is CD4; the disease is tuberculosis.