SLC7A10 and obesity due to melanocortin 4 receptor deficiency: Our data showed that active beige adipocytes carrying risk-free genotype had higher ETO-R oxygen consumption that reflects carbohydrate and amino acid utilization and expressed higher level of the neutral amino acid transporter, ASC-1 (encoded by SLC7A10) as compared to white or inactive beige adipocytes with the same TT genotypes, whereas there was no difference when the three types of adipocytes with FTO obesity-risk alleles were compared.