FTO and obesity due to melanocortin 4 receptor deficiency: We found a total of 172 genes that were expressed more in active as compared to inactive beige adipocytes carrying FTO risk-free variant, whereas only 18 genes were found in the same comparison with obesity-risk genotype carrier cells; nine genes were overlapping in the two comparisons (Supplementary Figure S3D; Supplementary Tables S9, S10).