This is in association with our previous study, which reported that the thermogenically prone human neck derived adipocytes carrying FTO obesity-risk genotype had lower expression of thermogenic genes, such as CKMT1A/B, CITED1, PPARGC1A/B, and CPT1B and genes involved in respiratory electron transport, fatty acid metabolism, and the signaling by retinoic acid pathways (Tóth et al., 2020). The gene discussed is PPARGC1A; the disease is Obesity.