Other thermogenic genes, such as UCP2, PM20D1, CIDEA, CITED1, CKMT1 and 2, CPT2, and PLIN1 were also expressed higher in active beige adipocytes carrying risk-free alleles as compared to white or inactive beige adipocytes with the same TT variant, however, we did not observe these differences in FTO obesity-risk carrier samples (Figures 3D–J). Here, FTO is linked to obesity due to melanocortin 4 receptor deficiency.