RNASE1 and neoplasm: To this end, we analyzed tumor-infiltrating cells among 4T1-vector, 4T1-vector plus compound 1, and 4T1-RNase1 tumors using mass cytometry by time-of-flight (CyTOF) 37, 38 with a panel of antibodies against various immune cell markers, followed by t-distributed stochastic neighbor embedding (t-SNE) 32 and FlowSOM 33 clustering analysis (Figure 2).