Without T cells' participation, the ectopic expression of RNase1 efficiently increased cancer cell growth in both BT-549-Vn and BT-549-αCD3 stable clones (Figure 5C, black vs. gray, red vs. blue, respectively), and BT-549-αCD3-R1 cells showed the lowest caspase-3/7-mediated cell death compared with the other stable clones (Figure 5D). The gene discussed is CASP3; the disease is cancer.