A recent study proved that miR-6836 was down regulated in exosomes of both osimertinib resistant plasma and M2 type tumor-associated macrophage (TAM) in non-small cell lung carcinoma and functioned via MSTRG.292666.16/miR-6386/MAPK8IP3 axis 31. This evidence concerns the gene MAPK8IP3 and non-small cell lung carcinoma.