ID1 and non-small cell lung carcinoma: ID1 was knocked down by shRNA in NADK-overexpressing H1299, A549, H157 and LN cells (Supplementary Fig. 5D), and the downregulation of ID1 in NSCLC cells impaired the anchorage-independent growth (Figure 6B-C) and migration (Figure 6D-E, Supplementary Fig. 5E) driven by the overexpression of NADK.