YBX1 and breast carcinoma: RT-PCR was conducted to examine YBX1 and hnRNPK implicated in RNA splicing regulation by virtue of AURKA mediation, which showed that YBX1 knockdown promoted GOLGA4 exon skipping, whereas hnRNPK knockdown promoted RBM4 exon inclusion in breast cancer cells (Fig. 3H–I).