Several genes related to other signaling pathways were over-expressed in both of the colon tumor cells under investigation: RIPK1, related to necroptosis (56), CDKN1A with a critical role in cell cycle arrest, GCLM, involved in glutathione biosynthesis, and SCL5A3 related to cellular responses to osmotic stress. Here, RIPK1 is linked to colonic neoplasm.