DAP3 and central nervous system cancer: Meanwhile, DAP3 is at the location of several important cellular pathways in tumorigenesis and has been shown to be expressed at elevated levels in aggressive glioblastoma cells and glioma cell lines with an induced migration phenotype [34]; survival analysis by Gera et al. [35] in a clinical study of a cohort of 127 breast cancer patients showed higher survival rates in the highly transcribed group.