In the inflammation-related lung cancer model induced by benzo(a)pyrene and lipopolysaccharide, NLRP3 and caspase-1 were colocated in the lung tissue of mice, but this phenomenon was not detected by NLRP6, indicating that the formation of NLRP3-dependent inflammasome promotes the occurrence of pulmonary inflammation-related tumors, but whether NLRP6 is involved in this process remains to be verified [81]. The gene discussed is NLRP3; the disease is lung carcinoma.