HLA-C*04:01 was protective for being a late-onset asthma case (OR = 0.25, 95%CI: 0.09 to 0.70) whereas HLA-B*40:02 and HLA-DRB1*04:05 increased the odds of being a case [(OR = 3.77, 95%CI: 1.91 to 7.44; OR = 8.19, 95%CI: 2.51 to 26.79), respectively]. Here, HLA-DRB1 is linked to asthma.