MAPK1 and cancer: In addition, the role of several genes that have been reported in other types of cancers remains to be explored in LUSC prognosis, such as mitogen-activated protein kinase 2 (MAPK2) [44], G protein signaling modulator 1 (GPSM1) [45, 46], tumor necrosis factor receptor superfamily member 8 (TNFRSF8; CD30) [47] and TNF receptor type 1 associated death domain protein (TRADD) [48].