The laboratory work-up showed leukocytosis (he had received G-CSF (filgrastim) prior to admission), 26,420 WBC/mL(90% neutrophils), and thrombocytopenia (140,000 platelets/mL), acute kidney injury, elevated lactate (2.7 mmol/L), D-Dimer (3.25 mg/L) and lipase (904 UL) and moderate microscopic hematuria. The gene discussed is CSF3; the disease is acute kidney injury.